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The BIOFIRE System and Your Immune System The BIOFIRE System offers syndromic testing for infectious diseases, allowing healthcare professionals to choose the appropriate test first time. Patients benefit from quicker diagnosis and more targeted treatment. Clinicians benefit from a better stewardship of antibiotics. Labs improve efficiency and cost savings. The BioFire Pneumonia Plus Panel (PN panel) analyzes native sputum (including mini-BAL) and endotracheal lavage and bronchoalveolar liquids (including mini BAL) for 33 clinically important pathogens and resistance genes to antimicrobials in one hour. Respiratory The burning of biomass (wood plants, agro-forestry and other organic materials) creates gaseous pollutants and fine particles of matter which negatively impact the respiratory system. Moreover, the environmental problems caused by forest fires, like droughts, may be potentiated by climate change, thereby increasing the negative effects on the health of humans. In the United States wildfire smoke is associated with hospitalizations for respiratory illnesses like asthma, COPD, and lung cancer. This kind of air pollution also increases the risk of developing cardiovascular disease and is a major cause of the burden of disease in the most vulnerable populations. During the COVID-19 pandemic, many communities were exposed levels of air pollution resulting from wildfires. However, bio ethanol fireplace uk to this environmental issue is sporadic and mainly focused on educating people about symptom management. This gap in knowledge is troubling due to the evidence of possible health risks from continued exposure to smoke and other sources of poor air quality. Researchers are now looking at the best ways to safeguard public health in future events of this type. NIH is funding research on this critical public health problem through the BLUE CORAL study as well as its successor FIRE CORAL. For the first time, a prospective study will evaluate long-term outcomes of exposure to smoke from wildfires and other sources. FIRE CORAL recruits adult participants who are hospitalized for COVID-19 index episodes and speak English or Spanish however, they are not pregnant. The protocol for Fire Coral includes a series of in-person assessments that objectively measure the pulmonary function testing lung imaging and functional assessment. The lungs are the most sensitive to the effects of smoke and other particles because they can trigger or exacerbate chronic respiratory illnesses, such as emphysema and COPD and increase the risk of contracting pneumonia. There are a variety of steps that can be taken to avoid or lessen the negative health effects from short-term exposures to smoke, which includes avoidance of outdoor activities whenever possible and using the EPA's “N95” mask designed to trap fine particles. Smoking can cause irritation to the eyes, throat and nose. To minimize symptoms, drink plenty of water, and take medicines that help reduce inflammation, like corticosteroids. Bloodstream Bloodstream is the first line of defense against germs that invade your system. Dendritic cells are specialized cells that are like your fire department's call centre; they gather antigens (molecules that trigger an immune response) from invaders and release proteins to signal other white blood cells to fight them. The total number of white blood cells, differentials, and band cells grew after firefighters' fire-fighting duties as compared to levels following strenuous exercise without fire-fighting. Skin Dermatologists were concerned that the smoke and ash from the California wildfires could cause negative effects on the skin of those who were exposed to these substances. Maria Wei is a graduate student at the University of California, Irvine. She investigates how the extreme pollution from wildfires impacts the skin. Her research was published in Scientific Reports on April 22nd. The study of Wei shows that the temperature changes of the skin depending on the length of time the body is exposed. It can take as long as two hours for the skin of an individual to reach its “flash point”—the point where it starts to burn and turn to ash. That's why it's important to stay away from a fire or campfire, and why you should wear protective clothing if you are outside during a forest fire or even a hot day. While it is important to be aware of the dangers of fire-related pollution, there's no way to stop forest fires from happening. Wei believes that as the climate changes cause forests to burn more, the number of people suffering from wildfires will increase. This means that more people will have to wear long sleeves and hats and thick moisturizers. It's also worth noting that atopic dermatitis (itchy skin) that many people suffer from can be exacerbated by the air pollution from wildfires. The particles in smoke can clog up pores, making atopic skin worse. Another issue is that atopic dermatitis tends to make people more sensitive to UV light, which may be aggravated by wildfire smoke. This makes people more likely to seek out tanning salons, and it can also cause the skin to get darker with less protection than they should. A treatment using ice and fire may help reduce atopic skin dermatitis symptoms, but it is not advised for anyone who has an open wound or rash. Patients who suffer from acne are advised to avoid it as well and if you're pregnant or breastfeeding it's recommended to avoid this treatment altogether. The IS Clinical Fire & Ice Facial is offered at Novuskin Las Vegas' premier membership MedSpa is a results-driven, intensive facial that bridges between a mild facelift and a peel, but without the need for any downtime. It is designed to resurface skin, reduce rosacea, reduce fine lines and acne scarring and also encourage cellular regeneration. It's an incredible treatment to give yourself an energizing glow. Infections The human body is a complex system of organs and tissues that work together to protect us from infections. Infections can be caused by microorganisms like parasites, viruses and bacteria that invade healthy cells and cause them to multiply in uncontrolled ways. Your immune system may react by displaying signs of illness. These symptoms could include a runny nose to a stomach that is upset as well as swelling of lymph glands, or a rash. The nature of the infection and its location can impact the symptoms. Infections can be spread in different ways, but the most common is via droplets of air that remain after sniffling or coughing. Bacterial diseases such as strep throat, tuberculosis, meningococcal disease, and Legionnaires' disease spread through this method, along with some viral infections, such as the common cold and influenza. Some bacterial infections such as skin infections or sexually transmitted diseases (STIs) like Chlamydia and gonorrhea can be transmitted through direct contact with affected tissues or mucous surfaces or indirectly through contaminated surfaces. Certain bacterial infections are carried by bugs like ticks, mosquitoes or fleas. They can be spread by bites from these bugs you. Viruses, parasites and other microorganisms are tiny enough that they can enter your bloodstream to infect your cells. This can lead to serious diseases like the common cold or AIDS. Fungi can cause skin conditions such as ringworm and athlete's foot and some can affect the respiratory tract and nervous system. The BioFire PN Panel utilizes our innovative FilmArray technology to test for a comprehensive list of pathogens involved in upper respiratory infections in sputum and samples of bronchoalveolar fluid. The kit comes with a reagent bag that contains all the chemistry necessary to perform reverse transcription as well as nested multiplex PCR detection in one machine. This is a simple method that helps clinicians identify and treat patients with various respiratory symptoms. This test has received an Emergency Use Authorization and is available through bioMerieux's CLIA moderate and high complexity labs.